alpha-MSH

A 13-amino acid peptide derived from proteolytic cleavage of ADRENOCORTICOTROPIC HORMONE, the N-terminal segment of ACTH. ACTH (1-13) is amidated at the C-terminal to form ACTH (1-13)NH2 which in turn is acetylated to form alpha-MSH in the secretory granules. Alpha-MSH stimulates the synthesis and distribution of MELANIN in MELANOCYTES in mammals and MELANOPHORES in lower vertebrates.

Also Known As:

(Des-Acetyl)-alpha-MSH; (Desacetyl)alpha-MSH; ACTH (1-13); ACTH (1-13)NH2; ACTH(1-13); Acetylated ACTH (1-13)NH2; Adrenocorticotropin (1-13)NH2; DE-alpha-MSH; Des-Acetyl MSH; Desacetyl alpha-MSH; Desacetyl alpha-Melanocyte-Stimulating Hormone; MSH, (Desacetyl)alpha-; alpha-Melanotropin; Desacetyl alpha MSH; Desacetyl alpha Melanocyte Stimulating Hormone; Hormone, Desacetyl alpha-Melanocyte-Stimulating; Hormone, alpha-Melanocyte-Stimulating; Intermedin, alpha; MSH, Des-Acetyl; alpha MSH; alpha Melanocyte Stimulating Hormone; alpha Melanotropin; alpha-MSH, Desacetyl; alpha-Melanocyte-Stimulating Hormone, Desacetyl; MSH, alpha; alpha Intermedin; alpha-Melanocyte-Stimulating Hormone

Pharmalogical Action Categories:

Hormones

Hormones, Hormone Substitutes, and Hormone Antagonists
- Hormones: 80400
  - Peptide Hormones: 1347
    - Pituitary Hormones: 601
      - Anterior Pituitary Hormones: 187
        Pro-Opiomelanocortin: 1936
        alpha-MSH: 968
        Melanocortins: 946
        Melanocyte-Stimulating Hormones: 1119
        alpha-MSH: 968
    - Hypothalamic Hormones: 68
      - Pro-Opiomelanocortin: 1936
        alpha-MSH: 968
        Melanocortins: 946
        Melanocyte-Stimulating Hormones: 1119
        alpha-MSH: 968
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Nerve Tissue Proteins: 2
    - Neuropeptides: 6772
      - Melanocyte-Stimulating Hormones: 1119
        alpha-MSH: 968
      - Hypothalamic Hormones: 68
        Pro-Opiomelanocortin: 1936
        alpha-MSH: 968
        Melanocortins: 946
        Melanocyte-Stimulating Hormones: 1119
        alpha-MSH: 968
- Peptides: 82426
  - Neuropeptides: 6772
    - Melanocyte-Stimulating Hormones: 1119
      - alpha-MSH: 968
    - Hypothalamic Hormones: 68
      - Pro-Opiomelanocortin: 1936
        alpha-MSH: 968
        Melanocortins: 946
        Melanocyte-Stimulating Hormones: 1119
        alpha-MSH: 968
  - Peptide Hormones: 1347
    - Pituitary Hormones: 601
      - Anterior Pituitary Hormones: 187
        Pro-Opiomelanocortin: 1936
        alpha-MSH: 968
        Melanocortins: 946
        Melanocyte-Stimulating Hormones: 1119
        alpha-MSH: 968
    - Hypothalamic Hormones: 68
      - Pro-Opiomelanocortin: 1936
        alpha-MSH: 968
        Melanocortins: 946
        Melanocyte-Stimulating Hormones: 1119
        alpha-MSH: 968

A P Friedman Selected Research

A P Friedman Research Topics

Disease

Drug/Important Bio-Agent (IBA)